Day: May 7, 2018

At a cellular and molecular level.

It has long been known that hormones such as progesterone and oestrogen encourage the proliferation of cancer cells. Because of this, probably the most common treatments is the administration of hormone receptor blockers. The block, however, affects all of the cells of the body not merely the cancer cells, and causes numerous side effects in patients. Additionally, melanoma develop resistance after time and development continues despite anti-hormone therapy. In order to treat these patients it is necessary to comprehend the mechanisms that trigger proliferation, to be able to inhibit them. The researchers from the Chromatin and Gene Expression lab at the CRG, led by Miguel Beato, focus on focusing on how hormones activate cell division in breast cancer, concentrating on regulating the expression of the genes that control the cell cycle. Read More